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VACCINES IN THE MANAGEMENT OF CANCER: where we are heading
FIRST WORKSHOP “Fondazione Piccoli Cuori Joy”
Saturday November, 15 and Sunday November, 16, 2008
Molecular Biotechnology Center, Aula Galileo, Via Nizza 52, 10126 Torino
PROGRAMME
Saturday, November 15
9,00-13,00 am
Logistics, aims and issues
Guido Forni, Torino, Italy
The role of NKT cell subsets in the regulation of tumor immunity
Jay Berzofsky, Bethesda, USA
Conditions for success of therapeutic vaccination against the oncongenic proteins of high risk Human Papilloma Virus
Kees Melief, Leiden, Netherlands
Peptide based vaccines in melanoma. Lessons and perspectives
Pedro Romero, Lausanne, Switzerland
High molecular weight melanoma-associated antigen, immunotherapy of malignant diseases and immune escape
Soldano Ferrone, Pittsburgh, USA
1,00-2,00 pm LUNCH
2,00- 6,30 pm
Cancer vaccines targeting key molecules in carcinogenesis: What have we learned during 15 years of clinical trials?
Gustav Gaudernack, Oslo, Norway
Prioritization of cancer antigens and immunotherapy agents for vaccine trials
Mac Cheever, Seattle, USA
Translational development of vaccines for hematologic cancers
Larry Kwak, MD Anderson, Houston, Texas
Concluding remarks and issues for tomorrow
Giorgio Inghirami, Torino, Italy
Sunday November 16
9,00 am-12,30 pm
HOW TO DESIGN A RATIONALE CLINICAL TRIAL FOR TESTING A NEW VACCINE:
between the idea and money
Chairman:
Giuseppe Masucci, Stockholm, Sweden
A discussion guided by:
Giuseppe Masucci, Stockholm, Sweden
Michael Papamichail, Athens, Greece
Federica Pericle, El Paso, Texas
Critical issues in clinical vaccine design
- Adjuvants
- Regulatory cells
- Suppressor activities
- Combination therapies
How to design a clinical trial:
- Number of patients,
- Time frame
- Clinical and surrogate end-points
- Should we get rid of Treg and myeloid suppressor cells?
- Combination therapies: are these possible in Phase I trials?
Who will sponsor a vaccine and a vaccine based trial?
Conclusions
INFORMATION
Participation is limited to 230 people.
Free entrance - must subscribe with on line registration.
Participation includes coffee breaks on Saturday and Sunday and lunch on Saturday.
An attendance certificate will be given at the end of the workshop.
Downloads
How to reach MBC .pdf  
Hotel .pdf
Flyer .pdf 
For further information: claudia.mondino@fobiotech.org
Fondazione per le Biotecnologie
Viale Settimio Severo 63 - 10133 Torino
tel 011 6600187, fax 011 6600708
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